The 58th Concurso Nacional de Belleza de Colombia (Señorita Colombia 2010) was held on 15 November 2010 at the Getsemaní Auditorium of the Julio César Turbay Ayala Convention Center in Cartagena de Indias, Colombia. During the election and coronation gala, Señorita Colombia 2009, Natalia Navarro Galvis, crowned Miss Valle, María Catalina Robayo Vargas, as her successor.