Miss República Dominicana 2006 was held on 2005-12-18 at the Palacio de los Deportes in Santo Domingo, República Dominicana, with 21 contestants. Mía Lourdes Taveras López of Santiago won the title and later represented the country at Miss Universo 2006 and Miss Continente Americano 2006. The event was broadcast by Telemicro and featured entertainment by Héctor Acosta.