Miss República Dominicana 2010 was held on April 17, 2010 at the Teatro La Fiesta of the Hotel Jaragua in Santo Domingo. Eva Arias of Espaillat won and represented the Dominican Republic at Miss Universe 2010. Other titleholders and runners-up were assigned to Miss Continente Américano 2010, Reina Hispanoamericana 2010, Miss Worldovision 2010, Miss Global Teen 2010, and Miss Intercontinental 2010.