Miss Venezuela 1981 was the 28th Miss Venezuela pageant, held at the Macuto Sheraton Hotel in Caraballeda, Vargas state, Venezuela, on May 7, 1981. It was broadcast live on Venevision, and at the end of the night outgoing titleholder Maye Brandt crowned Irene Sáez of Miranda as Miss Venezuela. Sáez later won Miss Universe 1981, while first runner-up Pilín León won Miss World 1981, marking Venezuela's first sweep of both major international pageant titles in the same year.