Señorita Panamá 2010 was the 27th Señorita Panamá and the 44th Miss Panamá pageant selecting Panama’s delegate to Miss Universe. The final took place at the Sheraton Hotel, Panama City, Panama, on July 8, 2010, and was broadcast by Telemetro. Ten contestants competed; Señorita Panamá 2009 Diana Broce crowned Anyolí Ábrego of Veraguas as the winner. Ábrego later represented Panama at Miss Universe 2010 in Las Vegas.