Miss Universe Panamá 2022 was the first Miss Universe Panamá pageant and the 56th Miss Panamá selection, held on May 25, 2022 to choose Panama’s representative to Miss Universe. It marked the debut of the renewed Miss Universe Panama Pageant after the Miss Universe Organization awarded the license to producer Ricardo Canto, the new director in 2022. Ten contestants competed; Brenda Andrea Smith Lezama (Miss Panamá Universe 2021) crowned Solaris De la Luna Barba Cañizales of Herrera as the winner.