Señorita Panamá 2024 was the 58th edition of the national pageant, held at the Figali Convention Center in Panama City on August 3, 2024. It was the first edition under the renewed organization led by Cesar Anel Rodríguez. Natasha Vargas (Miss Panamá 2023) crowned Italy Mora (Riviera del Canal) as Miss Universe Panama 2024, but Mora was later disqualified by the Miss Universe Organization. On April 22, 2025, the Señorita Panamá Organization named Mirna Caballini Bouche (Chiriquí) as the new Miss Universe Panama 2024 to represent the country at Miss Universe 2025. The edition featured 24 entrants and a Top 12 placement.